Clade I Mpox In The Democratic Republic Of The Congo And Neighboring Countries

Mpox Outbreak in the Democratic Republic of the Congo Raises Concerns

Clade I Strain Emerges as a Threat

The Democratic Republic of the Congo (DRC) is currently experiencing an outbreak of clade I mpox, formerly known as monkeypox. While clade I mpox is endemic to the DRC, the current outbreak has reached unprecedented levels.

Escalating Numbers and CFR

Since the publication of the Threat Assessment Brief in 2023, the number of mpox cases in the DRC has surged to 14,626, resulting in 654 deaths (CFR 4.5%). Clade I mpox is known to cause more severe illness than other clades, raising concerns among healthcare officials.

Genomic Features and Epidemiology

Epidemiological and genomic data from the outbreak in a mining region in the DRC suggest that the virus is spreading through close contact and contact with infected animals. The strain responsible for the outbreak is distinct from other clades of mpox, highlighting the need for further research and surveillance.

WHO Calls for Emergency Response

On August 7, 2024, the head of the World Health Organization (WHO) declared a public health emergency of international concern due to the escalating mpox outbreak in the DRC. The WHO is urging countries to strengthen surveillance, implement infection control measures, and provide equitable access to vaccines and treatments.

Conclusion

The mpox outbreak in the Democratic Republic of the Congo is a serious public health threat. The emergence of clade I mpox has heightened concern due to its potential for severe illness. The WHO's call for an emergency response underscores the need for international cooperation and urgent action to contain the outbreak and protect vulnerable populations.